Description
Acute rheumatic fever
An acute illness caused by an autoimmune response to infection with group A Streptococcus, leading to a range of possible symptoms and signs affecting any or all of heart, joints, brain, skin and subcutaneous tissues
Rheumatic carditis
Active inflammation of the heart tissues, most importantly the mitral and/or the aortic valves, caused by acute rheumatic fever. Rheumatic carditis can lead to chronic damage that remains after the acute inflammatory episode has resolved
Rheumatic heart disease
The persistent damage to heart valves resulting in mitral and/or aortic regurgitation, or in long-standing cases stenosis, that remains as a result of acute rheumatic fever with rheumatic carditis. Complications of rheumatic heart disease include heart failure, embolic stroke, endocarditis and atrial fibrillation.
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