Mehran Classification for In-Stent Restenosis (ISR) Mehran Classification for ISR Select ISR Pattern: Type I – Focal (≤10 mm in length) Type II – Diffuse Intrastent (>10 mm within the stent) Type III – Diffuse Proliferative (Extends beyond stent margins) Type IV – Total Occlusion (ISR with complete vessel occlusion) Submit